About PMI-DB

Summary of PMI-DB


Introduction of PMI-DB

Interactions between proteins and small molecule metabolites play a vital role in regulating protein functions and controlling various cellular processes. The activities of metabolic enzymes, transcription factors, transporters and membrane receptors all can be mediated through protein-metabolite interaction (PMI). The recent rapid development of large-scale mass spectrometry (MS) analysis on biomolecules have discovered large mount of PMIs.

PMIDB provides both interactions and non-interactions between protein and metabolite, which not only reduces the experimental cost for biological experimenters, but also facilitates the construction of more accurate algorithms for researchers using machine learning. PMIDB provides a user-friendly interface for browsing the biological function of the metabolites/proteins of interest, experimental technology for identifying PMIs, PMIs in different species, which provides important support for further understanding of cellular processes.

Overview of PMI-DB


Figure 1. Proportion of entries of species


Figure 2. Proportion of entries of different detection technologies


Figure 3. The number of PMIs by different detection technologies


Figure 4. The number of PMIs for each metabolites

  What can users do with PMI-DB

  • Browsing for the PMIs of interested species;
  • Searching for interactions between metabolites and interested proteins;
  • Searching for interactions between proteins and interested metabolites;
  • Browsing different approaches for detecting PMIs;

  Metabolites

  Release & Version

  • Paper name

  Statistics

  Reference database

  Visitors

  Cite & contact